Drug Repurposing
Drug Repurposing refers to studying existing medical knowledge and technologies that are already approved for treating a particular disease or condition to see if they are safe and effective for treating other conditions/diseases. Pharmaceutical and biotech companies are increasingly relying upon repurposing of drugs to treat both, common as well as, rare diseases since the same involves the use of de-risked compounds with lower development timelines and costs involved.
Molecular Connections’ Drug Repurposing Service helps pharmaceutical and biotech companies overcome major technological and regulatory challenges that need to be addressed while ensuring safe and successful drug formulations. Our team of experts and custom workflows, specifically designed for Drug Repurposing, help explore multiple data sources to extract entities related to a particular drug.
Select Case Studies
- Exploring the role of Histone deacetylases (HDACs) in Neoplasms and use of their inhibitors in cancer treatment.
In this case study we identified frequently occurring neoplasms associated with HDAC-altered expression, drugs being used as HDAC inhibitors, and the processes encompassed by drugs to inhibit HDAC. - Understanding pharmacologic actions, protein interactions and toxicity studies using XTractorTM.
In this case study we extracted the pharmacological actions, protein interactions and toxicity of various drugs and we also manually curated the side-effects from the drug labels.
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